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Have gout? Help control the root cause of gout with ULORIC

Let's start with a fun little fact: ULORIC is the first FDA-approved branded prescription medicine for lowering uric acid, in adults with gout, in more than 40 years! That said, you're probably wondering about ULORIC, what it does, and how it works to help lower your uric acid levels.

ULORIC Reduces Uric Acid in Adults with Gout

Gout is caused by a buildup of uric acid. Uric acid comes from substances called purines. As much as two thirds of uric acid is made naturally by your body. The remaining third comes from some of the things you eat and drink.

Most people are able to rid their bodies of uric acid. But, if your body produces too much uric acid and/or has a difficult time getting rid of uric acid, it builds up in your blood to higher-than-healthy levels. If you have gout, high uric acid can lead to more attacks.

ULORIC works by stopping the body from turning purines into uric acid. As a result, uric acid levels stay low in most gout patients over time. Research shows that if you have gout, keeping your uric acid level low can help control your gout symptoms over time.

ULORIC has been proven to help gout patients control the root cause of gout

For long-term management of gout, your uric acid level should be less than 6 mg/dL.

In clinical studies:

  • ULORIC was shown to be effective in lowering uric acid to healthy levels (less than 6 mg/dL).
  • When ULORIC was compared to allopurinol, another medicine often used to lower uric acid:
    • As many patients on ULORIC 40 mg reached a healthy uric acid level as allopurinol.
    • Up to twice as many patients on ULORIC 80 mg reached a healthy uric acid level as allopurinol.

See more on how ULORIC and allopurinol differ. Don't forget to talk with your healthcare professional about whether ULORIC should be part of your gout treatment plan.


Treating the root cause of gout or just the pain?

Pain relief is an important first step, but, there are 2 steps to managing gout: pain relief and treating the root cause of gout, high uric acid levels in the blood. ULORIC can help adults with gout lower uric acid to a healthy level (less than 6 mg/dL).

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Use of ULORIC

ULORIC is a prescription medicine used to lower blood uric acid levels in adults with gout. ULORIC is not for the treatment of high uric acid without a history of gout.

Individual results may vary.

Important Safety Information

Do not take ULORIC if you are taking Azathioprine, Mercaptopurine, or Theophylline.

For some people, gout may flare up when starting certain gout medicines, including ULORIC. If you have a flare while taking ULORIC, do not stop taking your medicine. Your healthcare provider may give you other medicines to help prevent your gout flares.

A small number of heart attacks, strokes, and heart-related deaths were seen in clinical studies. It is not certain that ULORIC caused these events.

Your healthcare professional may do blood tests to check your liver function while you are taking ULORIC.

Tell your healthcare professional about liver or kidney problems or a history of heart disease or stroke.

The most common side effects of ULORIC are liver problems, nausea, gout flares, joint pain, and rash.

Please see the complete Prescribing Information and talk to your healthcare professional.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

ULORIC® is a registered trademark of Teijin Pharma Limited and used under license by Takeda Pharmaceuticals America, Inc.
All other trademark names are the property of their respective owners.
©2010 Takeda Pharmaceuticals North America, Inc.
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