How Does ULORIC Work?

ULORIC helps reduce your gout's root cause to a more manageable size

Let’s start with a fun little fact: ULORIC is the first FDA-approved branded prescription medicine for lowering uric acid in adults with gout in more than 40 years! That said, you’re probably wondering more about ULORIC, what it does, and how it works to help lower your uric acid levels.

What Is ULORIC?

ULORIC is a prescription medicine that lowers uric acid levels in adults with gout. ULORIC is not for the treatment of high uric acid without a history of gout.

The root cause of gout is high uric acid. ULORIC works by stopping the body from turning purines into uric acid to help you reach a healthy level (less than 6 mg/dL).

If your healthcare professional prescribes ULORIC, you should take it every day to help lower your uric acid level and keep it low over time. Individual results may vary.

Your gout may flare up when you start taking ULORIC. If you have a flare while taking ULORIC, do not stop taking your medicine. Your healthcare professional may tell you to take other medicines to help prevent or manage gout flares during initial treatment.

ULORIC May Work for You

Research shows keeping your uric acid level low (less than 6 mg/dL) can reduce future gout attacks over time. If you have gout, ULORIC can help you control your uric acid.

In clinical studies:

  • ULORIC was proven effective in lowering uric acid to healthy levels
    (less than 6 mg/dL).
  • When ULORIC was compared with allopurinol, another medicine often used to lower uric acid:
    • As many patients on ULORIC 40 mg reached a healthy uric acid level as those on allopurinol.
    • Up to twice as many patients on ULORIC 80 mg reached a healthy uric acid level as those on allopurinol.
  • ULORIC has been studied in more than 4000 patients, in some for more than five years.
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ULORIC Is Simple to Take

  • One 40 mg or 80 mg pill daily.
  • You can take ULORIC with or without food.
  • You can take ULORIC with antacids.
  • You can take ULORIC without changing your dose if you are taking certain common medications, including:
    • Colchicine
    • Naproxen (Aleve®, Naprosyn)
    • Indomethacin (Indocin)
    • Hydrochlorothiazide (Aquazide H, HydroDIURIL)
    • Warfarin (Coumadin)
    • Desipramine (Norpramin)
  • Your healthcare professional may do blood tests to check your liver function while you are taking ULORIC.
  • Be sure to take ULORIC as your healthcare professional tells you
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Use of ULORIC

ULORIC is a prescription medicine used to lower blood uric acid levels in adults with gout. ULORIC is not for the treatment of high uric acid without a history of gout.

Individual results may vary.

Important Safety Information

Do not take ULORIC if you are taking Azathioprine or Mercaptopurine.

Your gout may flare up when you start taking ULORIC; do not stop taking your ULORIC even if you have a flare. Your healthcare provider may give you other medicines to help prevent your gout flares.

A small number of heart attacks, strokes, and heart-related deaths were seen in clinical studies. It is not certain that ULORIC caused these events.

Tell your healthcare professional about liver or kidney problems or a history of heart disease or stroke.

Your healthcare professional may do blood tests to check your liver function while you are taking ULORIC.

The most common side effects of ULORIC are liver problems, nausea, gout flares, joint pain, and rash.

Please see the complete Prescribing Information and talk to your healthcare professional.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

ULORIC is a trademark of Teijin Pharma Limited registered with the U.S. Patent and Trademark Office and used under license by Takeda Pharmaceuticals America, Inc.
©2011 Takeda Pharmaceuticals North America, Inc.

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