Safety & Side Effects
Understanding ULORIC—Safety & Side Effects
If you’re beginning treatment with ULORIC, it’s important to know that it has been studied extensively, in multiple clinical studies; more than 4000 patients with gout took part in them—some for more than 5 years. In fact, these studies comprised the largest clinical studies of gout patients ever. See how ULORIC measured up—review some of the findings from clinical studies.
Possible Side Effects
ULORIC may cause side effects in some people. The most common side effects are:
- Liver problems
- Gout flares
- Joint pain
Your healthcare professional may do blood tests to check your liver function while you are taking ULORIC.
A small number of heart attacks, strokes and heart-related deaths were seen in clinical studies. It is not certain that ULORIC caused these events.
Tell your healthcare professional about liver or kidney problems or a history of heart disease or stroke.
Tell your healthcare professional if you develop a rash, have any side effect that bothers you, or that does not go away.
These are not all of the possible side effects of ULORIC. For more information, ask your healthcare professional or download our Prescribing Information.
What If I Experience a Gout Flare While Taking ULORIC?
Gout may flare up when you start taking medicine (e.g., ULORIC, allopurinol, and probenecid) to lower your uric acid. This may be caused when crystals begin to dissolve in your joints as your uric acid level goes down. Your healthcare professional may tell you to take other medicines to help prevent or manage flares during initial treatment. If your healthcare professional gives you medicine to lower your uric acid, you should keep taking it, even between attacks.
To determine the right gout treatment plan for you, talk with your healthcare professional.
ULORIC and Other Medications
Be sure to tell your healthcare provider about any medications, vitamins, or nutritional supplements you’re taking. There are certain types of medications that shouldn’t be taken with ULORIC. These include:
If you have gout and you’re taking colchicine, naproxen, indomethacin, hydrochlorothiazide, or warfarin, your healthcare professional can still prescribe ULORIC along with these medicines without worrying about switching medicines or changing the dose.
What Dose Should I Take?
ULORIC is available in two doses: 40 mg or 80 mg once daily. Talk with your healthcare professional about which dose is right for you.
Patients with mild to moderate kidney or liver problems can take the same dose of ULORIC as anyone else.* Older patients can take the same doses, too.
*Only a small number of patients with severe kidney problems were studied with ULORIC. Patients with severe liver problems were not studied.
This information does not take the place of talking with your healthcare professional about your medical condition or your treatment.
Next: Getting Started With ULORIC >