Glossary – Definitions of Gout-related Terms

anti-inflammatory: (an-tee-in-flam-uh-tawr-ee, an-tie-in-flam-uh-tawr-ee) medication that works to reduce inflammation (including swelling, warmth, redness, and pain)

crash diet: common expression for a diet designed to cause quick weight loss

crystals (urate): solid objects formed by repeating a three-dimensional pattern; uric acid deposits composed of salt crystals are formed from uric acid

deformities: changes from the normal shape or size of body parts resulting in disfigurement

disability: impairment that interferes with normal function

hyperuricemia: (hi-per-yuri-seem-ee-uh) an abnormally high level of uric acid in the blood

inflammation: (in-fluh-mey-shuhn) a reaction that causes pain, redness, and/or swelling in a part of the body that reacts to infection, irritation, or injury

nonprescription: available without a doctor's written approval, including over-the-counter medicines

obesity: condition of being very overweight

progression: the way in which a disease develops over time

purines: (pyoor-eens) a substance found naturally in the body's tissues, as well as in certain foods and beverages; when the body processes, or breaks down, purines, the resulting product is uric acid

risk factor: a condition or activity that makes a harmful event more likely

uric acid: final product from the breakdown of purines, which is eliminated from the body in urine

well-balanced diet: an eating plan that includes all basic nutritional elements

ULORIC is a prescription medicine used to lower blood uric acid levels in adults with gout. ULORIC is not for the treatment of high uric acid without a history of gout.

Individual results may vary.

Do not take ULORIC if you are taking Azathioprine, Mercaptopurine, or Theophylline.

For some people, gout may flare up when starting certain gout medicines, including ULORIC. If you have a flare while taking ULORIC, do not stop taking your medicine. Your healthcare provider may give you other medicines to help prevent your gout flares.

A small number of heart attacks, strokes, and heart-related deaths were seen in clinical studies. It is not certain that ULORIC caused these events.

Your healthcare professional may do blood tests to check your liver function while you are taking ULORIC.

Tell your healthcare professional about liver or kidney problems or a history of heart disease or stroke.

The most common side effects of ULORIC are liver problems, nausea, gout flares, joint pain, and rash.

Please see the complete Prescribing Information and talk to your healthcare professional.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.