What Is Gout?

Gout is a painful form of arthritis with attacks commonly felt in a big toe or other joints.

  • Gout is caused by hyperuricemia, which is a buildup of uric acid in the body.
  • High uric acid can form crystals in your joints, and can lead to extremely painful gout attacks.

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Lower Uric Levels Below 6 mg/dL

To help reduce future gout attacks, it’s important to lower your uric acid level to a healthy level (less than 6 mg/dL)

What Is Uric Acid?

Uric acid is created when the body breaks down substances called purines. Purines are found in body tissues as well as in some foods and drinks.

Purines are an important part of the cells in your body, and are broken down and reused in the body through a process known as purine metabolism. Uric acid is produced as a result of purine metabolism, and is circulated within the bloodstream.

There will always be a certain amount of uric acid in the blood as it is thought to have important functions in the body, but excess uric acid in the blood will be removed as waste. Diets consisting of food and drinks that are high in purines may cause an imbalance in the body where higher amounts of uric acid are being produced, but not enough is getting removed as waste. This imbalance can lead to higher than normal uric acid levels in the blood, which can form crystals and result in painful gout attacks.

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Discuss Gout with Your Doctor

This downloadable Doctor Discussion Guide can help get the conversation going.

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Important Safety Information for Uloric (febuxostat)

Do not take Uloric if you are taking azathioprine or mercaptopurine.

Uloric may cause serious side effects, including:

Gout Flares. Gout flares can happen when you first start taking Uloric. Your healthcare provider may give you other medicines to help prevent your gout flares.

Heart Problems. People who take Uloric can have serious heart problems including heart attacks, strokes and heart-related deaths. It is not known that Uloric caused these problems. Call your healthcare provider right away or get emergency medical help if you have any of the following symptoms: chest pain, shortness of breath, dizziness, numbness or weakness on one side of your body, trouble talking or headache.

Liver Problems. Liver problems can happen in people who take Uloric. Your healthcare provider may do blood tests to check how well your liver is working before and during your treatment with Uloric.

Severe Skin and Allergic Reactions. Serious skin and allergic reactions that may affect different parts of the body such as your liver, kidneys, heart or lungs, can happen in people who take Uloric. Call your healthcare provider right away or get emergency medical help if you have any of the following symptoms: rash, red and painful skin, severe skin blisters, peeling skin, sores around the lips, eyes or mouth, swollen face, lips, mouth, tongue or throat, or flu-like symptoms.

The most common side effects of Uloric include liver problems, nausea, gout flares, joint pain, and rash. Tell your healthcare provider if you have any side effect that bothers you, or that does not go away.

Use of Uloric

Uloric is a prescription medicine used to lower blood uric acid levels in adults with gout. Uloric is not for the treatment of high uric acid without a history of gout.

Individual results may vary.

Please see the complete Prescribing Information and talk to your healthcare professional.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Important Safety Information for Uloric (febuxostat)

Do not take Uloric if you are taking azathioprine or mercaptopurine.

Uloric may cause serious side effects, including:

Gout Flares. Gout flares can happen when you first start taking Uloric. Your healthcare provider may give you other medicines to help prevent your gout flares.

Heart Problems. People who take Uloric can have serious heart problems including heart attacks, strokes and heart-related deaths. It is not known that Uloric caused these problems. Call your healthcare provider right away or get emergency medical help if you have any of the following symptoms: chest pain, shortness of breath, dizziness, numbness or weakness on one side of your body, trouble talking or headache.

Liver Problems. Liver problems can happen in people who take Uloric. Your healthcare provider may do blood tests to check how well your liver is working before and during your treatment with Uloric.

Severe Skin and Allergic Reactions. Serious skin and allergic reactions that may affect different parts of the body such as your liver, kidneys, heart or lungs, can happen in people who take Uloric. Call your healthcare provider right away or get emergency medical help if you have any of the following symptoms: rash, red and painful skin, severe skin blisters, peeling skin, sores around the lips, eyes or mouth, swollen face, lips, mouth, tongue or throat, or flu-like symptoms.

The most common side effects of Uloric include liver problems, nausea, gout flares, joint pain, and rash. Tell your healthcare provider if you have any side effect that bothers you, or that does not go away.

Use of Uloric

Uloric is a prescription medicine used to lower blood uric acid levels in adults with gout. Uloric is not for the treatment of high uric acid without a history of gout.

Individual results may vary.

Please see the complete Prescribing Information and talk to your healthcare professional.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.