Why ULORIC?

ULORIC can help you stand up to gout by lowering your uric acid level. Individual results may vary.

Gout is a painful form of arthritis caused by a buildup of uric acid. If you have gout, high uric acid buildup can lead to gout attacks. For the treatment of gout in most people, the goal is to get uric acid levels below 6 mg/dL, which can help reduce future attacks. Learn more about gout and uric acid here.

ULORIC is a treatment option for gout patients that works by lowering their uric acid level, the root cause of gout.

ULORIC vs Allopurinol

ULORIC can offer some key differences compared to allopurinol

ULORIC was proven superior to allopurinol, an older gout medicine, in multiple studiesars ULORIC was proven superior to allopurinol, an older gout medicine, in multiple studiesars

*Based on results combined across three phase 3 studies ranging from 6-12 months; ULORIC 40 mg was only included in one of the studies, and ULORIC 80 mg and allopurinol were included in each of the studies.

Clinical studies comparing ULORIC and allopurinol for the treatment of gout found that

  • 7 out of 10 gout patients taking ULORIC 80 mg reached a target uric acid level, less than 6 mg/dL*
  • As many patients on ULORIC 40 mg reached a healthy uric acid level as those on allopurinol

ULORIC offers some key differences in patients with mild to moderate kidney problems

  • More patients with mild to moderate kidney problems reached a healthy uric acid level (less than 6 mg/dL) while taking ULORIC compared with allopurinol
  • Unlike patients using allopurinol, patients with mild to moderate kidney problems do not have to change doses with ULORIC. Only a small number of patients with severe kidney problems were studied. If you have kidney problems, ask your healthcare professional about the differences between medicines used to lower uric acid levels
ULORIC Safety Profile

ULORIC has an established safety profile

ULORIC has been studied extensively, in multiple clinical studies; more than 4000 patients took part in them—some for more than 5 years.

ULORIC has been studied in patients like you

ULORIC clinical studies included gout patients that were also dealing with a kidney problem called chronic kidney disease (CKD) stage 2 or 3 (59%). Only a small number of patients with severe kidney problems were studied. If you have kidney problems, talk to your healthcare professional.

Possible side effects

The most common side effects include:

  • Liver problems
  • Nausea
  • Gout flares
  • Joint pain
  • Rash

Your healthcare professional may do blood tests to check your liver function while you are taking ULORIC.

A small number of heart attacks, strokes, and heart-related deaths were seen in clinical studies. It is not certain that ULORIC caused these events.

Tell your healthcare professional about liver or kidney problems or a history of heart disease or stroke.

Tell your healthcare professional if you develop a rash or have any side effect that bothers you or that does not go away. These are not all of the possible side effects of ULORIC.  For more information, ask your healthcare professional or download our Prescribing Information.

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Important Safety Information
for ULORIC

Important Safety Information for ULORIC

Do not take ULORIC (febuxostat) if you are taking Azathioprine or Mercaptopurine.

Your gout may flare up when you start taking ULORIC; do not stop taking your ULORIC even if you have a flare. Your healthcare provider may give you other medicines to help prevent your gout flares.

A small number of heart attacks, strokes, and heart-related deaths were seen in clinical studies. It is not certain that ULORIC caused these events.

Tell your healthcare professional about liver or kidney problems or a history of heart disease or stroke.

Your healthcare professional may do blood tests to check your liver function while you are taking ULORIC.

The most common side effects of ULORIC are liver problems, nausea, gout flares, joint pain, and rash.

Use of ULORIC

ULORIC is a prescription medicine used to lower blood uric acid levels in adults with gout. ULORIC is not for the treatment of high uric acid without a history of gout.

Individual results may vary.

Please see the complete Prescribing Information and talk to your healthcare professional.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.